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MDD STUDY 2

RELMADA DEPRESSION STUDY

RESEARCH STUDY

What is this study investigating?

To evaluate the therapeutic efficacy of REL-1017 (Esmethadone) as an adjunctive treatment compared to placebo with antidepressant therapy.

What is Esmethadone?: Esmethadone is an NMDAR blocker, that is taken in the form of an oral pill. Blocking hyperactive NMDAR channels represents a novel approach to treating depression with a mechanism that is different from the classes of currently approved drugs.  Through early clinical trials, we have seen this medication has a low affinity for respiratory depression and addiction.

Overview: This is a 28-day long study with a 2 week follow up phase. 7 in-office visits are required for the first 4 weeks, and 4 in-office visits are required for the 2-week follow up phase.

You May Qualify If:

  • You are 18 to 65 years of age
  • You are currently on an oral antidepressant medication
  • You are still experiencing symptoms of depression

Qualified candidates may be compensated $50 per visit.

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